Thirteen years after surviving a devastating orbital disaster, astronaut Ryan Stone trains a new generation aboard ISS-2, including Ava Kowalski, daughter of legendary astronaut Matt Kowalski. When a catastrophic debris collision destroys the station, the crew faces a desperate fight for survival. Trapped in the unforgiving vastness of space, Ava must overcome impossible odds, confront the cost of survival, and discover what it truly means to carry on her father's legacy.